RAD51C polyclonal antibody
产品名称： RAD51C polyclonal antibody
英文名称： RAD51C polyclonal antibody
产品编号： PAB6271
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of RAD51C.
- Immunogen:
- A synthetic peptide corresponding to human RAD51C.
- Sequence:
- RGKTFRFEMQRDL-C
- Host:
- Goat
- Theoretical MW (kDa):
- 14.9, 42.2
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize all three human isoforms.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes.
Dosanjh MK, Collins DW, Fan W, Lennon GG, Albala JS, Shen Z, Schild D.Nucleic Acids Res. 1998 Mar 1;26(5):1179-84.
- Entrez GeneID:
- 5889
- Protein Accession#:
- NP_002867;NP_478123;NP_478124
- Gene Name:
- RAD51C
- Gene Alias:
- MGC104277,RAD51L2
- Gene Description:
- RAD51 homolog C (S. cerevisiae)
- Omim ID:
- 602774
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- DNA repair protein RAD51 homolog 3,RAD51 homolog C,RAD51 homolog C, isoform 1,yeast RAD51 homolog 3
- Gene Pathway